International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Seminar Infection Diseases in Arctic

Comparative analysis of climatic-geographicae zones’ autopsus in different periods of time can reveal peculiarities in a disease, such as turerculosis, at some particular stage of its course. In other words, the analysis can reveal the pathomorphosis, which is very important.

Theoretical prerequisites, materials and methods are expounded in the monograph “Pathomorphosis and pathological anatomy of pulmonary consumption in Yakutia at the end of the 20th century”, K.G.Basharin, M., Isdatelstvo Academii nauk o Zemle, 2001, 95s.

The purpose of this paper is to give a comparative analysis of immediate causes of deaths of lung tuberculosis in pre-antibacterial and antibacterial periods in Yakutia, the largest region in the North. We’ve analysed autopsies of lung patients in Yakutsk prefecture with in the time span of 15 years. This lime span was divided in to two periods: the ferst, pre-antibacterial, from 1946 to 1950 (556 autopsies); the second, antibacterial (compresing two feve-years parts: from 1963 to 1967 (222 autopsies), and from 1982 to 1986 (221 autopsy).

The data of the analysis are as follows. During the ferst, pre-antibacterial period 94,9% of the patients died of the main tubercular course and its specific complications, but not of non-specific causes (such as inadequacy of the lung heart (0,9%); the organs amyloidosis (2,6%); pulmonary haemmorhage (1,4%). During the second, antibacterial period the immediate cause of death in lung patients underwent considerable chandes. In the first five-year part of the antibacterial period, in 30,6% of the immediate causes of deaths in lung patients were the main tubercular course and its specific complications; this is three times less than in the pre-antibacterial period. The number of non-specific complications, which were immediate causes of deaths in lung patients, increased thirteenfold, as compared with the pre-antibacterial period; and comprised 69,4% of all autopsies.

In 1982-1986 in comparison with 1963-1967 there was a slight increase of deaths due to the disease course progressing and non-specific complications (42,1% against 31,1%). The increase of deaths of emaciation was also noted – 9,9% of all autopsies.

Thus, comparative analysis of the autopsies revealed the fact, that in Yakutia there took peace a pathomorphosis of immediate causes of deaths in lung patients. It consists in the following: in the first, pre-antibacterial period (1946-1950) patients died of the main course of the disease and its specific complications (94,9%); whereas in the antibacterial period (1963-1967, 1982-1986) they died mainly of non-specific complications (68,9% and 57,9% accordingly). The acquired data will help promote modern diagnostics and effective treatment of lethal complications.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)