International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Ethnic peculiarities of the North native inhabitants health

Aim. To study the influence of Helicobacter Pylori (НР) eradication on the frequency of ulcer disease relapse.

Methods. We examined 140 patients with duodenum ulcer disease (93 male, 47 female). 101 subjects (Group I, 57 subjects with non-complicated cause; Group II, 44 subjects with ulcer hemorrhages) were provided with HP eradication by 7-day schedule: omeprasol (20mg x 2 times) + claritromicin (500 mg х 2 times) + amoksicillin 1g х 2 times). HP was diagnosed by morphological and urease techniques. 39 subjects (Group III, 24 subjects with ulcer hemorrhages; Group IV, 15 subjects with non-complicated cause) made control group, HP eradication wasn’t carried out. Monitoring was made during 18 months.

Results. The efficiency of HP eradication made 88.6% in Group I and 89.5% in Group II. Acute ulcer disease during 18 months was marked in 27.% subjects in Group I and in 17.5% subjects in Group II, in 83.3% subjects in Group III (р<0.01) in 73.3% subjects in Group IV (р<0.01). During the reported period ulcer hemorrhages were not marked in Group I and Group II , their frequency in Group III and IV was 10.3% (р<0.05).

Conclusion. HP eradication is an effective means of ulcer diseases prophylaxis, with its complications in Eastern Siberia inhabitants.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)