International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Ethnic peculiarities of the North native inhabitants health

The autonomic nervous system innervates internal organs and blood vessels and determines their function. The important role in realization of adaptive reactions under complex climatic conditions belongs to a sympathetic section of the autonomic nervous system.

The present research is aimed at the study of morphogenesis of ganglia of sympathetic trunk of people living in conditions of Siberia during the pre- and postnatal periods of ontogenesis. Ganglia of human sympathetic trunk in different age groups were taken as the material for investigation. Histological study followed by morphometric and statistical processing has been carried out. It is revealed that ganglia’s morphogenesis of human sympathetic trunk is characterized by change in heterogeneity of cells population and alternation of the periods of acceleration and deceleration. In different age periods ganglia differ in the compactness of cells location and the development of connective tissue streaks. The difference in neuronal-glial interrelations and the development of the simple and specialized interneural contacts has been revealed. It has been found that in young people neurons and gliocytes of sympathetic ganglia have the largest total area, while in old people the neurons’ area and their density in the unit of tissue decrease that results in the enlargement of connective tissue.

Structural-functional formation of neurons depends on their vascular-trophic provision: the formation of bloodstream and glial capsules correlate with the neurons’ maturation. Visualization and the extension of capillary-glio-neurocellular contacts are maximal in foetuses, however the estimated neuron-glial index characterizing the neurons’ trophism has its maximum in the nodes of the young people that coincides with the period of the highest functional activity.

In the structural organization of ganglia of sympathetic trunk a cranial-caudal gradient has been revealed showing the reduction of the neurons and gliocytes total area as well as the capillary density that correlates with smaller functional load of low ganglia in human sympathetic trunk.

Thus, the study carried out has shown that the structural maturation of sympathetic ganglia takes place during ontogenesis. The functional stability of sympathetic ganglia is reached in the young people who are the most resistant to the impact of adverse factors of Siberian region.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)