International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Ecology and adaptation (medical ecology)

The data of scientific studies show a serious problem of human health and survival in the Far North, connected with disadaptive meteopathic disturbances in cardio-vascular system, occurring and developing under the influence of the extreme helio-geophysical and climatic-meteorological factors. In our works it has been shown, that pathological meteosensitivity is an independent risk-factor of cardio-vascular pathology (Hasnulin V.I., Hasnulina A.V., Sevostyanova E.V., 2004). It is known, that psychophysiological adaptation is the most important component of the whole adaptive process. Just “breakages” in psychophysiological adaptation lead to the development of meteopathies.

The aim of the investigation was to study disturbances of psychophysiological adaptation to the complex of geo-ecological factors of the North at the development of cardio-vascular pathology. The complex clinico-psychophysiological investigation of 196 persons – patients with chronic cardio-vascular pathology (arterial hypertension, coronary artery disease) – inhabitants of high latitudes (the republic SAHA) was carried out. Control groups included 65 healthy persons-inhabitants of moderate latitudes (Novosibirsk) and 83 healthy persons - inhabitants of high latitudes (Norilsk). Determination of levels of pathological meteosensitivity, functional disturbances, estimation of psychophysiological characteristics were carried out with the use of original computer program “SCREENMED”. Functional activity of cerebral hemispheres and functional interhemispheres asymmetry were valued according to intensity of blood circulation in the cerebral hemispheres (rheoencephalography in H. H. Yarullin`s method).

It has been shown reliable (p<0,01) increase in the level of pathological meteosensitivity in patients with cardio-vascular pathology as compared with healthy persons. Statistically reliable (p<0,05) direct correlations between levels of pathological meteosensitivity and cardio-vascular disturbances have been revealed.

The results of the investigation have shown, that the degree and frequency of pathological meteoreacting depend on the functional state of the main regulatory systems and, first of all, on the state of central nervous system. Persons with some innate or acquired “weakness” of nervous system, with disturbances in dynamic of cortex processes with the prevalence of reflexes inhibition, and also persons in the state of psychoemotional stress appeared to be the most meteosensitive. These persons were characterized by the increased level of psychoemotional tension, decreased sensomotor reactivity and mental capability for work, desynchronization of endogenous rhythms with outer geo-ecological rhythms. The reliable (p<0,05) decrease in functional activity of cerebral hemispheres, mainly the right one, has been revealed in meteosensitive patients with cardio-vascular pathology. Functional activity of the right hemisphere in patients with high level of pathological meteosensitivity was reliably lower, than in patients with low level of meteosensitivity. Indices of psychoemotional stress in the examined persons correlated with decrease in functional activity of cerebral hemispheres, mainly the right one. Manifestations of psychoemotional instability and pathological meteosensitivity have been found reliably (p<0,05) more frequent in patients with the left cerebral hemisphere prevalence. Not only the prevalence of the right or left hemisphere, but the degree of functional interhemisphere asymmetry were of great importance. An increase in functional asymmetry in the case of the left hemisphere prevalence led to an increase in psychoemotional stressing and disadaptation to the changing factors of the environment.

In the whole, the investigation has revealed the most important psychophysiological mechanisms of cardiometeopathies` development. The results of the study should be used in the programs of preserving human life and health in the Far North.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)