International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Behavioral Health

Background and Purpose: We sought to examine the relationship between depression symptoms and the risk development of cardiovascular diseases among men ages 25 to 64 years. Methods and materials: Within the framework of program WHO MONICA-MOPSY was examined representative sample of men 25-64 years old (1994 year). Total sample was 657 persons. Depression symptoms were measured at baseline with the use of the MONICA - psychosocial Interview Depression scale. The incidence of news arterial hypertension, myocardial infarction and stroke was ascertained under systematic surveillance the 10-year follow-up. Cox - proportional regression model was used for an estimation of relative risk (RR). Results: Prevalence of depression in cohort of men with arterial hypertension was - 28.9%, with myocardial infarction - 65.8% and the most high depression level was of men with stroke – 70.6%. The relative risk of development of arterial hypertension within 5 years in group of men with high level of depressive symptoms, in compared with those with low depressive symptoms was 6.7 times higher (95% confidence interval (CI)= 3.56-8.23; р<0.05). The relative risk of MI for the depression group was 2.26 (95% CI=1.25- 4.63,p<0,01).The relative risk of incident ischemic stroke was 6.4 (95% CI= 3.97 – 7.58, p<0,001) for those who showed symptoms of depression compared with those who did not. Within 10 years RR of development cardiovascular diseases has decreased of men with high level of depressive symptoms for development arterial hypertension (RR=4.2 (95% CI =2.5- 6.17) for myocardial infarction – (RR=2.4 (95% CI =1.5- 3.89, and stroke – RR=5.2 (95% CI, 3.6 – 6.91)(p<0.05). Conclusion: Depression is a predictor of cardiovascular diseases in middle-age men.

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Last update: 06-Jul-2012 (11:52:05)