International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Environmental health

Aim. To study the indices of Helicobacter Pilory (НР) dissemination in stomach cancer patients in Khakassia.

Methods. We examined 79 Europoids in Khakassia Republican Oncological Hospital with verified diagnosis of stomach cancer. Proximal localization of the pathology was determined in 39 patients, and distal in 40. We examined 52 healthy subject as a control group. We determined IgG Cag A of HP in all the subjects by serologic methods in blood serum. Bacteria were registered in all the subjects in antral part of stomach by morphological and urease methods including the calculation of dissemination density.

Results. НР was determined by morphological and urease methods in mucous in antral part of stomach in 71.8% subjects with paroximal cancer, in 92.5% subjects with distal cancer ( P<0.05) and in 78.2% healthy subjects. IgG Cag A of HP were diagnosed in 58% subjects with proximal localization, in 80.0% subjects with distal localization of cancer (P<0.05) and in 59.6% subjects of control group. НР dissemination density was 68% higher in subjects with distal cancer as compared with proximal localization of the pathology.

Conclusion. Cag A of HP and HP dissemination indices in mucous of antral part of stomach are associated with distal localization of stomach cancer. The indices of HP dissemination in proximal localization patients do not differ from those in control group.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)