International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Cardiovascular diseases

Metabolic syndrome (MS) is one of the main risk factors of CVD. The symptoms of MS appear long before the vascular dramatic event develops: in adolescents, when there is a combination of unfavorable genetic factors and unhealthy life style.

The aim of the study: to investigate the prevalence of some components (hypertriglyceridemia, hypo-α-cholesterinemia, elevated blood pressure (BP), overweight) of MS in adolescents 14-17 years of age in Novosibirsk.

Methods: Representative samples of adolescent population 14-17 years of age both sexes were investigated in Novosibirsk. During 15 years (1989-2003) there were investigated 2569 adolescents (1212 boys and 1354 girls). The response was 88,6%-93,8%. The prevalence of the components of MS was estimated according to the following criteria: hypertriglyceridemia with the meaning of TG≥ 100 mg/dl, hypo-α-cholesterinemia with the meaning of high-density lipoprotein cholesterol (HDL-C) ≤ 40mg/dl, elevated BP registered if BP was higher then the 90th percentile of distribution, overweight was fixed when Ketle index was more then 85 percentile. The existence of any three and more components is enough to diagnose MS.

Results: Population frequency of hypertriglyceridemia in boys was 17%, in girls – 15,6%. The prevalence of hypo-α-cholesterinemia in boys was higher than in girls (16,7% and 6,7%, р<0,05). The prevalence of elevated systolic BP and diastolic BP was similar (10-11%). 1310 examined adolescents (51%) (of total number 2379) had none of the studied components of MS (48% of boys and 53,4% of girls),14,6% of the adolescents had 2 components (15,1% of boys, 14,1% of girls), 3 components of MS were in 2,3% of adolescents (boys – 3,4%, girls – 1,4%), and 6 adolescents had 4 components (0,2%). The frequency of hypertriglyceridemia was high in both sex groups as compared with other studied components.

Conclusions: The prevalence of MS (3 and more components) was 3,4% in boys and 1,4% in girls. The prevalence of MS in adolescents in our study is comparable with the data of other authors (S.Cook, M.Weitzman, 2003; AyeT, LevitskyL, 2003).

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)