International Union for Circumpolar Health Ministry of Public Health and Social Development of RF Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Medical Sciences Siberian Branch of Russian Academy of Sciences Medical Polar Fund “Science” The Northern Forum

Abstracts

Cardiovascular diseases

The development of arterial hypertension (AH) is determined by set of cooperating risk factors, which require correction cause of high prevalence of given cardiovascular pathology and its insufficient control. Alongside with genetic, somatic, social and economic factors unfavorable climate and geographic factors of the environment, in particular ecological conditions of such regions as Siberia and the Far North , heavily influence the development and progressing of AH.

The disturbance of photoperiodicity, the difference of atmospheric pressure, low temperature, hypocynesia are referred to such factors. It is proved that in given territories the existence of iodine deficiency in biosphere causes growth of occurrence of thyroid gland diseases disturbances of functional condition of which intensify the course of somatic pathology in particular AH.

113 patients (men and women between 30 and 67 years old) hospitalised in clinic of SCCEM SD RAMS with diagnosis of AH 2-3 degree, constantly living in Western-Yakut industrial region (Mirnyi, Mirninsky area) and middle zone of Western Siberia (Novosibirsk, Novosibirsk region) were examined, their condition of hormone status was evaluated and thyroid gland was echoscanned.

1 group consisted of patients only with AH (n=66), 2 group consisted of patients with thyroid gland pathology revealed at the examination (n=47): nodular euthyroid goiter (n=20) and autoimmune thyroiditis (n=27). At the examination of sexual structure it is shown that in the second group there were mainly women (89,4%) and in the first group the number of men and women was equally (43,9% and 56,1% accordingly). The analysis was carried out in a place of constant residence of examined patients. In the first group of patients the correlation of the number of inhabitants of Western-Yakut industrial region to the number of inhabitants of middle zone of Western Siberia was 1: 2.9 and in the group of patients with combined pathology was 1: 1.4. Consequently among patients with AH and thyroid gland pathology persons living in Western-Yakut industrial region were met in 1.6 times more frequently against to patients only with AH. At the estimation of difficulty of the course of hypertonia depending on the existence of thyroid gland pathology it is revealed that 3 degree of AH was met in 3.5 times more frequently, tendency toward the increase of revelation frequency of hypertonic crisis combined with cardiovascular pathology was traced in group of patients with combined pathology in comparison with group of patients only with AH. The insufficiency of blood circulation developed in 4 times more frequently in group of patients with combined pathology. More high degree of blood pressure was registered in group of patients with AH and thyroid gland pathology in comparison with group of patients with AH ( the median index was 170/100 mm torr. And 150/100 mm torr., max level – 180/110 and 170/100 accordingly). Thus, the received results show that thyroid pathology complicates the course of AH.

The received results have allowed to formulate criteria for allocation of group of risk of occurrence and heavier course of AH: a female, menopause, diseases of thyroid gland, constantly residing in the regions of the Far North.

Note. Abstracts are published in author's edition

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Last update: 06-Jul-2012 (11:52:05)